Genetic blueprint of the zoonotic pathogen Toxocara canis

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Genetic blueprint of the zoonotic pathogen Toxocara canis

Toxocara canis is a zoonotic parasite of major socioeconomic importance worldwide. In humans, this nematode causes disease (toxocariasis) mainly in the under-privileged communities in developed and developing countries. Although relatively well studied from clinical and epidemiological perspectives, to date, there has been no global investigation of the molecular biology of this parasite. Here ...

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Toxocara canis and Toxocara catis

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Adult Toxocara canis encephalitis.

A 48-year-old patient with Toxocara canis infection developed severe ataxia, rigor and neuropsychological disturbances. An aetiology was proven by an indirect immunofluorescence test. CT and MRI revealed both diffuse and circumscribed white matter lesions. Angiography showed multiple occlusion of branches of the middle cerebral artery. Anthelminthic treatment was beneficial in the initial stage...

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The Mitochondrial Genome of Toxocara canis

Toxocara canis (Ascaridida: Nematoda), which parasitizes (at the adult stage) the small intestine of canids, can be transmitted to a range of other mammals, including humans, and can cause the disease toxocariasis. Despite its significance as a pathogen, the genetics, epidemiology and biology of this parasite remain poorly understood. In addition, the zoonotic potential of related species of To...

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MR in Toxocara canis myelopathy.

We present the case of a 23-year-old woman with cerebrospinal fluid eosinophilia and myelopathy caused by Toxocara canis and describe the clinical and thoracic MR findings. An enhancing thoracic spinal cord lesion which was shown on MR resolved after an interval of 140 days with partial resolution of the patient's symptoms.

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ژورنال

عنوان ژورنال: Nature Communications

سال: 2015

ISSN: 2041-1723

DOI: 10.1038/ncomms7145